Polynucleotide (PN)
An Innovation for Cellular Skin Rejuvenation and Deep Skin Nourishment
Problems such as wrinkles, acne scars, enlarged pores, and skin deterioration can occur for many reasons. These issues are signs that our skin needs proper care. Today, there are many ways to address these concerns. Polynucleotide (PN) has become one of the most recognized Skin Booster innovations because of its ability to rejuvenate the skin at the cellular level, repairing and nourishing the skin effectively from within.
What is Polynucleotide (PN Skin Booster)?
Polynucleotide (PN) is a biomolecule composed of nucleotide subunits, which are the fundamental building blocks of DNA and RNA. It is extracted from purified salmon or trout DNA. This substance has a structure similar and highly compatible with human DNA, making it suitable for injection into the skin for rejuvenation without triggering an immune response. It acts as a biostimulator that promotes the skin’s natural regeneration process.
Individual results may vary.
How Does Polynucleotide (PN) Work?
When Polynucleotide enters the skin layer, it initiates biological mechanisms at the cellular level that promote skin regeneration and repair.
Stimulates Fibroblasts and Increases Collagen Production
Polynucleotide promotes the growth and activity of fibroblasts in the dermal layer, which is the primary source of collagen production in the skin. It also inhibits MMP-1, an enzyme responsible for collagen degradation, while enhancing new collagen synthesis.
Stimulates Adenosine A2A
Polynucleotide activates Adenosine A2A receptors, which help inhibit inflammatory processes and collagen breakdown. It stimulates the production of anti-inflammatory cytokines, a group of small proteins involved in regulating and suppressing inflammation. It also plays an important role in the formation of new blood vessels, improving blood circulation and the delivery of oxygen and nutrients to skin tissues.
Delivers Essential Building Blocks Directly to Cells
Aging skin cells and cells exposed to stress often have difficulty synthesizing new nucleotides. Polynucleotide directly supplies genetic components, enabling fibroblasts to repair DNA and restore cellular structure immediately.
Individual results may vary.
Why Choose Polynucleotide (PN Skin Booster) at Remede Wellness Clinic?
At Remede Wellness Clinic, our experienced medical team will guide you through every step, from in-depth consultation to follow-up care, ensuring you receive the highest standard of treatment.
We understand that every individual has unique skin concerns and goals. Therefore, we provide personalized treatments and products tailored to each patient to achieve the highest level of satisfaction. The clinic combines modern medicine with complementary medical approaches and advanced technology to deliver the best possible results.
Who Is Polynucleotide (PN) Suitable For?
✔️ Individuals with fine lines and deep wrinkles.
✔️ Individuals with loose or sagging skin.
✔️ Individuals with dry, dehydrated, and dull skin.
✔️ Individuals with uneven skin tone or redness.
✔️ Individuals seeking improvement in delicate areas such as the under-eye region.
✔️ Individuals who want to repair skin damaged by sunlight or pollution.
✔️ Minimal Downtime, No Recovery Needed
✔️ Individuals seeking natural and long-lasting results.
Individual results may vary.
Key Advantages of Polynucleotide (PN)
Polynucleotide has gained popularity because it supports skin regeneration from within and delivers natural-looking results.
• Stimulates internal regeneration by activating natural cellular repair and renewal processes.
• Low risk, as PN is derived from salmon or trout DNA, which is highly similar to human DNA and therefore less likely to cause allergic reactions.
• Provides natural-looking results by stimulating the body’s own collagen and elastin production.
What Can Polynucleotide (PN) Help With?
• Improves skin hydration, elasticity, and wrinkles, resulting in a more youthful appearance through collagen and elastin stimulation.
• Reduces acne scars, wrinkles, and dullness, making the skin smoother, brighter, and more even-toned.
• Helps soothe sensitive skin by enhancing hydration, reducing dryness, and improving skin resilience.
• Accelerates wound healing after aesthetic procedures by promoting re-epithelialization, reducing redness, and improving scar appearance.
• Improves under-eye concerns, including dark circles and under-eye bags.
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Treatment performed by licensed doctor. Results shown are based on individual cases and may vary
Individual results may vary.
Treatment performed by licensed doctor. Results shown are based on individual cases and may vary
Are There Any Precautions with Polynucleotide (PN)?
Although Polynucleotide is considered highly safe, there are certain precautions:
• Individuals with a fish allergy should avoid PN treatment because it is commonly derived from salmon or trout DNA.
• Pregnant or breastfeeding women should avoid treatment for safety reasons.
• Individuals with skin infections in the treatment area should resolve the infection before treatment.
• Temporary side effects may include swelling, redness, bruising, or small bumps at the injection site, which usually disappear within a few hours to a few days.
A consultation with a qualified physician is recommended to evaluate skin condition and determine treatment suitability.
What Is the Treatment Process for Polynucleotide (PN)?
1. Consultation: The physician evaluates skin condition, concerns, and treatment goals to create an appropriate treatment plan.
2. Cleansing: The treatment area is thoroughly cleansed.
3. Topical Anesthetic: A numbing cream is applied to minimize discomfort during treatment.
4. PN Injection: The physician injects PN into the dermis using an appropriate technique, either with a fine needle or a cannula, depending on the treatment area and medical judgment.
5. Cold Compress: A cold compress may be applied after injection to reduce swelling and redness.
6. Post-Treatment Instructions: The physician provides aftercare recommendations, such as avoiding makeup, touching the skin, excessive sun exposure, and certain skincare products.
Typically, PN treatment is performed as a course of 2–3 sessions spaced approximately 2–4 weeks apart for optimal results. Maintenance treatments may be recommended periodically.
Individual results may vary.
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Frequently asked questions (FAQ)
Possible Side Effects of Polynucleotide (PN)
Side effects are generally mild and temporary, including small injection-site bumps, bruising, redness, swelling, pain, or irritation.
What Is the Difference Between PN and PDRN?
Polynucleotide (PN) and Polydeoxyribonucleotide (PDRN) belong to the same family of substances but differ in molecular structure, molecular weight, and certain properties.
PN has a higher molecular weight and longer molecular chains than PDRN. As a result, it is more effective at stimulating collagen and elastin production and provides more sustainable skin structural rejuvenation. PDRN is more commonly used for wound healing and inflammation reduction.
What Is the Difference Between PN and Hyaluronic Acid (HA)?
Both Polynucleotide (PN) and Hyaluronic Acid (HA) are used for skin rejuvenation, but they work differently and provide different benefits.
HA functions as a humectant that attracts and retains water in the skin, providing immediate plumping and hydration. However, it does not directly stimulate cellular repair or new collagen production like PN. PN focuses on skin regeneration and repair at the cellular level, resulting in more sustainable improvements and enhanced overall skin quality.
Remede's Polynucleotide Program: Why It's the Best
Skin Repair and Regeneration
Salmon DNA Concentration promotes cellular regeneration and accelerates the skin’s natural healing process, which leads to significantly improved skin texture and the reduction of fine lines. This process helps to rejuvenate the skin, giving it a more youthful and revitalized appearance over time.
Improved Skin Hydration
The treatment enhances the skin's ability to retain moisture, providing deep hydration that leaves the skin with a radiant and healthy glow. This increased hydration is particularly beneficial for those with dry or dehydrated skin, as it helps to plump the skin and reduce the appearance of fine lines and wrinkles.
Enhanced Skin Elasticity
By stimulating collagen production, Polynucleotides (PN) helps to restore skin elasticity and firmness, which contributes to a lifted and more resilient complexion. This treatment effectively combats sagging and loss of firmness, resulting in a more defined and youthful facial contour.
Experienced Professionals
Our team at Remede Wellness Clinic consists of highly trained and experienced professionals who have years of experienced in Collagen-Stimulating Injectables.
"We are committed to providing a top-notch Collagen-Stimulating Injectables focused on safety, efficacy, and patient comfort. Our experienced staff, detailed procedures, and the use of clean, sterile equipment ensure the best possible outcomes for our patients."